You test protein expression on a sample of circulating tumor cells isolated from a patient with breast cancer. Which of the following do you expect to see in the circulating tumor cells in comparison to the original tumor? (1pt) A) Increased expression of E-cadherin B) Increased expression of 1 and 3 integrins C) Reduced expression of MMPs D) Reduced Rho GTPase expression E) Reduced expression of Claudins/Occludins